ABSTRACT

Observation:

Papillon-Lefevre syndrome is a rare autosomal recessive disorder characterized by diffuse palmaplantar hyperkeratosis combined with early loss of primary and permanent teeth. Abdominal epilepsy is a rare condition most frequently found in children, consisting of gastrointestinal disturbances caused by epileptiform seizure activity. Extremely limited number of palmoplantar keratoderma cases associated with epilepsy was reported in the literature. Here we are presenting a case of PLS with abdominal epilepsy that to our knowledge has never been previously reported.