Case Report

A Case of Etanercept Induced Palmoplantar Pustular Psoriasis

Zennure Takçı^1*, Gülçin Güler Şimşek², Özlem Tekin¹

¹ Departments of Dermatology and

² Pathology, Ankara Keçiören Research and Training Hospital, Ankara, Turkey

Anahtar Kelimeler: TNF-α antagonistetanerceptadverse effectpsoriasispalmoplantar pustular psoriasis

Keywords: TNF-α antagonistetanerceptadverse effectpsoriasispalmoplantar pustular psoriasis

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Abstract

ABSTRACT

Observations:

Etanercept is a human recombinant soluble tumor necrosis factor  (TNF-α) receptor fusion protein. Etanercept has been used successfully to treat a wide range of inflammatory disorders including psoriasis and psoriatic arthritis resistant to classical disease-modifying treatments. The widespread use of TNF-α antagonists led to the recognition of adverse effects. Herein, we report a case of palmoplantar pustular psoriasis in a 37-year-old man during the etanercept therapy.