Hyperimmunglobulin E Syndrome with Severe Cold Abcesses

Hyperimmunoglobulin E syndrome is an immundeficiency disease characterized by recurrent pyogenic infections and periferic eosinophilia. It may be sporadic or with autosomal dominant transmission. Cold abscesses seen in patients are pathognomonic for this disease. This paper reports a 4-year-old male patient having severe cold abscesses in inguinal region, both thighs, and below umbilicus. On examination and laboratory investigation, there were pneumonia, high IgE levels and eosinophilia. Staphylococcus aureus growth occurred in culture from wound and blood and the patient was given antibiotherapy accordingly.